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Coactivation of estrogen receptor and IKK-β induces a dormant metastatic phenotype in ER-positive breast cancer

A growing body of evidence suggests that the inflammatory NFκB pathway is associated with the progression of ER+ tumors to more aggressive stages. However, it is unknown whether NFκB is a driver or a consequence of aggressive ER+ disease. To investigate this question, we developed breast cancer cell...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: El-Shennawy, Lamiaa, Dubrovskyi, Oleksii, Kastrati, Irida, Danes, Jeanne M., Zhang, Yiqun, Whiteley, Herbert E., Creighton, Chad J., Frasor, Jonna
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815896/
https://ncbi.nlm.nih.gov/pubmed/29229606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1686
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