Caricamento...
Targeting dynamic ATP-binding site features allows discrimination between highly homologous protein kinases
ATP-competitive inhibitors that demonstrate exquisite selectivity for specific members of the human kinome have been developed. Despite this success, the identification of highly selective inhibitors is still very challenging, and it is often not possible to rationally engineer selectivity between t...
Salvato in:
| Pubblicato in: | ACS Chem Biol |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6642640/ https://ncbi.nlm.nih.gov/pubmed/31038916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00214 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|