The Progress of CRISPR/Cas9-Mediated Gene Editing in Generating Mouse/Zebrafish Models of Human Skeletal Diseases

Genetic factors play a substantial role in the etiology of skeletal diseases, which involve 1) defects in skeletal development, including intramembranous ossification and endochondral ossification; 2) defects in skeletal metabolism, including late bone growth and bone remodeling; 3) defects in early...

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Dettagli Bibliografici
Pubblicato in:Comput Struct Biotechnol J
Autori principali: Wu, Nan, Liu, Bowen, Du, Huakang, Zhao, Sen, Li, Yaqi, Cheng, Xi, Wang, Shengru, Lin, Jiachen, Zhou, Junde, Qiu, Guixing, Wu, Zhihong, Zhang, Jianguo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2019
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Review Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639410/
https://ncbi.nlm.nih.gov/pubmed/31360334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.06.006
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