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Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation
CCR4-NOT is a conserved multiprotein complex which regulates eukaryotic gene expression principally via shortening of poly(A) tails of messenger RNA or deadenylation. Here, we reconstitute a complete, recombinant human CCR4-NOT complex. Our reconstitution strategy permits strict compositional contro...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6639331/ https://ncbi.nlm.nih.gov/pubmed/31320642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11094-z |
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