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Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos

Nanos proteins repress the expression of target mRNAs by recruiting effector complexes through non‐conserved N‐terminal regions. In vertebrates, Nanos proteins interact with the NOT1 subunit of the CCR4–NOT effector complex through a NOT1 interacting motif (NIM), which is absent in Nanos orthologs f...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Raisch, Tobias, Bhandari, Dipankar, Sabath, Kevin, Helms, Sigrun, Valkov, Eugene, Weichenrieder, Oliver, Izaurralde, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207322/
https://ncbi.nlm.nih.gov/pubmed/26968986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593634
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