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Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos

Nanos proteins repress the expression of target mRNAs by recruiting effector complexes through non‐conserved N‐terminal regions. In vertebrates, Nanos proteins interact with the NOT1 subunit of the CCR4–NOT effector complex through a NOT1 interacting motif (NIM), which is absent in Nanos orthologs f...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Raisch, Tobias, Bhandari, Dipankar, Sabath, Kevin, Helms, Sigrun, Valkov, Eugene, Weichenrieder, Oliver, Izaurralde, Elisa
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207322/
https://ncbi.nlm.nih.gov/pubmed/26968986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593634
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