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Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs
Pumilio is an RNA-binding protein that represses a network of mRNAs to control embryogenesis, stem cell fate, fertility and neurological functions in Drosophila. We sought to identify the mechanism of Pumilio-mediated repression and find that it accelerates degradation of target mRNAs, mediated by t...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7038932/ https://ncbi.nlm.nih.gov/pubmed/31863588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1187 |
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