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Mutations in Translation Initiation Factors Lead to Increased Rates of Deadenylation and Decapping of mRNAs in Saccharomyces cerevisiae

The turnover of most mRNAs in Saccharomyces cerevisiae begins with deadenylation followed by decapping and 5′→3′ exonucleolytic digestion. An important question involves the mechanisms that allow particular mRNAs to exhibit different rates of both deadenylation and decapping. Since the cap structure...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schwartz, David C., Parker, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84368/
https://ncbi.nlm.nih.gov/pubmed/10409716
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