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Mutations in Translation Initiation Factors Lead to Increased Rates of Deadenylation and Decapping of mRNAs in Saccharomyces cerevisiae

The turnover of most mRNAs in Saccharomyces cerevisiae begins with deadenylation followed by decapping and 5′→3′ exonucleolytic digestion. An important question involves the mechanisms that allow particular mRNAs to exhibit different rates of both deadenylation and decapping. Since the cap structure...

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Hlavní autoři: Schwartz, David C., Parker, Roy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC84368/
https://ncbi.nlm.nih.gov/pubmed/10409716
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