Mutations in Translation Initiation Factors Lead to Increased Rates of Deadenylation and Decapping of mRNAs in Saccharomyces cerevisiae

The turnover of most mRNAs in Saccharomyces cerevisiae begins with deadenylation followed by decapping and 5′→3′ exonucleolytic digestion. An important question involves the mechanisms that allow particular mRNAs to exhibit different rates of both deadenylation and decapping. Since the cap structure...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Schwartz, David C., Parker, Roy
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1999
Schlagworte:	Gene Expression
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10409716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.8.5247
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