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CD4(+) T Cells Drive Lung Disease Enhancement Induced by Immunization with Suboptimal Doses of Respiratory Syncytial Virus Fusion Protein in the Mouse Model

Respiratory syncytial virus (RSV) infection of seronegative children previously immunized with formalin-inactivated (FI) RSV has been associated with serious enhanced respiratory disease (ERD). The phenomenon was reproduced in the cotton rat and the mouse, and both preclinical models have been routi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Virol
मुख्य लेखकों: Schneider-Ohrum, Kirsten, Snell Bennett, Angie, Rajani, Gaurav Manohar, Hostetler, Leigh, Maynard, Sean K., Lazzaro, Michelle, Cheng, Lily I., O’Day, Terrence, Cayatte, Corinne
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639276/
https://ncbi.nlm.nih.gov/pubmed/31092578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00695-19
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