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Inferior immunogenicity and efficacy of respiratory syncytial virus fusion protein-based subunit vaccine candidates in aged versus young mice

Respiratory syncytial virus (RSV) is recognized as an important cause of lower and upper respiratory tract infections in older adults, and a successful vaccine would substantially lower morbidity and mortality in this age group. Recently, two vaccine candidates based on soluble purified glycoprotein...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cayatte, Corinne, Snell Bennett, Angie, Rajani, Gaurav Manohar, Hostetler, Leigh, Maynard, Sean K., Lazzaro, Michelle, McTamney, Patrick, Ren, Kuishu, O’Day, Terrence, McCarthy, Michael P., Schneider-Ohrum, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705161/
https://ncbi.nlm.nih.gov/pubmed/29182682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188708
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