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CD4(+) T Cells Drive Lung Disease Enhancement Induced by Immunization with Suboptimal Doses of Respiratory Syncytial Virus Fusion Protein in the Mouse Model

Respiratory syncytial virus (RSV) infection of seronegative children previously immunized with formalin-inactivated (FI) RSV has been associated with serious enhanced respiratory disease (ERD). The phenomenon was reproduced in the cotton rat and the mouse, and both preclinical models have been routi...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Schneider-Ohrum, Kirsten, Snell Bennett, Angie, Rajani, Gaurav Manohar, Hostetler, Leigh, Maynard, Sean K., Lazzaro, Michelle, Cheng, Lily I., O’Day, Terrence, Cayatte, Corinne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639276/
https://ncbi.nlm.nih.gov/pubmed/31092578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00695-19
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