Androgen Deprivation Leads to Increased Carbohydrate Metabolism and Hexokinase 2 Mediated Survival in Pten/Tp53 Deficient Prostate Cancer

Prostate cancer is characterized by a dependence upon androgen receptor (AR) signaling, and androgen deprivation therapy (ADT) is the accepted treatment for progressive prostate cancer. Although ADT is usually initially effective, acquired resistance, termed castrate resistant prostate cancer (CRPC)...

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Martin, Philip L., Yin, Juan-Juan, Seng, Victoria, Casey, Orla, Corey, Eva, Morrissey, Colm, Simpson, R. Mark, Kelly, Kathleen
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639059/
https://ncbi.nlm.nih.gov/pubmed/27375016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.223
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