Highly Selective and Potent Human β-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure-Activity Relationship Studies

Antzeko izenburuak

• Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes
  nork: Ghosh, Arun K., et al.
  Argitaratua: (2016)
• Design, synthesis, and X-ray structural studies of BACE-1 Inhibitors containing substituted 2-oxopiperazines as P1′-P2′ ligands
  nork: Ghosh, Arun K., et al.
  Argitaratua: (2017)
• Asymmetric Diels–Alder reaction of 3-(acyloxy)acryloyl oxazolidinones: optically active synthesis of a high-affinity ligand for potent HIV-1 protease inhibitors
  nork: Ghosh, Arun K., et al.
  Argitaratua: (2019)
• Structure-Based Design, Synthesis, and Biological Evaluation of Dihydroquinazoline-Derived Potent β-Secretase Inhibitors
  nork: Ghosh, Arun K., et al.
  Argitaratua: (2012)
• Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand
  nork: Ghosh, Arun K., et al.
  Argitaratua: (2018)