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Asymmetric Diels–Alder reaction of 3-(acyloxy)acryloyl oxazolidinones: optically active synthesis of a high-affinity ligand for potent HIV-1 protease inhibitors
We describe here our investigation of the asymmetric Diels–Alder reaction of chiral 3-(acyloxy)acryloyl oxazolidinones as dienophiles in various Lewis-acid promoted reactions with cyclopentadiene. The resulting highly functionalized cycloadducts are useful intermediates for the synthesis, particular...
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| Udgivet i: | RSC Adv |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society of Chemistry
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7351138/ https://ncbi.nlm.nih.gov/pubmed/32655859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ra10178k |
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