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Powerful testing via hierarchical linkage disequilibrium in haplotype association studies

Marginal tests based on individual SNPs are routinely used in genetic association studies. Studies have shown that haplotype‐based methods may provide more power in disease mapping than methods based on single markers when, for example, multiple disease‐susceptibility variants occur within the same...

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Detalhes bibliográficos
Publicado no:Biom J
Main Authors: Balliu, Brunilda, Houwing‐Duistermaat, Jeanine J., Böhringer, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637384/
https://ncbi.nlm.nih.gov/pubmed/30693553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201800053
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