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Powerful testing via hierarchical linkage disequilibrium in haplotype association studies

Marginal tests based on individual SNPs are routinely used in genetic association studies. Studies have shown that haplotype‐based methods may provide more power in disease mapping than methods based on single markers when, for example, multiple disease‐susceptibility variants occur within the same...

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書目詳細資料
發表在:Biom J
Main Authors: Balliu, Brunilda, Houwing‐Duistermaat, Jeanine J., Böhringer, Stefan
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637384/
https://ncbi.nlm.nih.gov/pubmed/30693553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201800053
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