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Combining information from linkage and association mapping for next-generation sequencing longitudinal family data
In this analysis, we investigate the contributions that linkage-based methods, such as identical-by-descent mapping, can make to association mapping to identify rare variants in next-generation sequencing data. First, we identify regions in which cases share more segments identical-by-descent around...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143620/ https://ncbi.nlm.nih.gov/pubmed/25519382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S34 |
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