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Pathway analysis for family data using nested random-effects models

Recently we proposed a novel two-step approach to test for pathway effects in disease progression. The goal of this approach is to study the joint effect of multiple single-nucleotide polymorphisms that belong to certain genes. By using random effects, our approach acknowledges the correlations with...

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Detalhes bibliográficos
Principais autores: Houwing-Duistermaat, Jeanine J, Uh, Hae-Won, Tsonaka, Roula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287857/
https://ncbi.nlm.nih.gov/pubmed/22373228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S22
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