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Combining information from linkage and association mapping for next-generation sequencing longitudinal family data

In this analysis, we investigate the contributions that linkage-based methods, such as identical-by-descent mapping, can make to association mapping to identify rare variants in next-generation sequencing data. First, we identify regions in which cases share more segments identical-by-descent around...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Balliu, Brunilda, Uh, Hae-Won, Tsonaka, Roula, Boehringer, Stefan, Helmer, Quinta, Houwing-Duistermaat, Jeanine J
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143620/
https://ncbi.nlm.nih.gov/pubmed/25519382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S34
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