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Testing for Genetic Association in the Presence of Linkage and Gene Covariate Interactions
In order to study family based association in the presence of linkage we extend a generalized linear mixed model proposed for genetic linkage analysis (Lebrec and van Houwelingen, 2007) by adding a genotypic effect to the mean. The corresponding score test is a weighted FBAT statistic, where the wei...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410551/ https://ncbi.nlm.nih.gov/pubmed/20166130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.200900057 |
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