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The Trimmed-Haplotype Test for Linkage Disequilibrium

Single-marker linkage-disequilibrium (LD) methods cannot fully describe disequilibrium in an entire chromosomal region surrounding a disease allele. With the advent of myriad tightly linked microsatellite markers, we have an opportunity to extend LD analysis from single markers to multiple-marker ha...

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Autors principals: MacLean, Charles J., Martin, Rory B., Sham, Pak C., Wang, Huan, Straub, Richard E., Kendler, Kenneth S.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288142/
https://ncbi.nlm.nih.gov/pubmed/10712218
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