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IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their re-anchoring into mitotic spindles

To build and maintain mitotic spindle architecture, molecular motors exert spatially regulated forces on microtubules (MT) minus-ends. This spatial regulation is required to allow proper chromosomes alignment through the organization of kinetochore fibers (k-fibers). NuMA was recently shown to targe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Taulet, Nicolas, Douanier, Audrey, Vitre, Benjamin, Anguille, Christelle, Maurin, Justine, Dromard, Yann, Georget, Virginie, Delaval, Benedicte
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635507/
https://ncbi.nlm.nih.gov/pubmed/31312011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46605-x
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