טוען...
A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53(wt) osteosarcoma cells
The p53 protein is engaged in the repair of DNA mutations and elimination of heavily damaged cells, providing anti-cancer protection. Dysregulation of p53 activity is a crucial step in carcinogenesis. This dysregulation is often caused by the overexpression of negative regulators of p53, among which...
שמור ב:
| הוצא לאור ב: | FEBS J |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6634946/ https://ncbi.nlm.nih.gov/pubmed/30715803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14774 |
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