Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne

Urine is increasingly being considered as a source of biomarker development in Duchenne Muscular Dystrophy (DMD), a severe, life-limiting disorder that affects approximately 1 in 4500 boys. In this study, we considered the mdx mice—a murine model of DMD—to discover biomarkers of disease, as well as...

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Veröffentlicht in:PLoS One
Hauptverfasser: Thangarajh, Mathula, Zhang, Aiping, Gill, Kirandeep, Ressom, Habtom W., Li, Zhenzhi, Varghese, Rency S., Hoffman, Eric P., Nagaraju, Kanneboyina, Hathout, Yetrib, Boca, Simina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634414/
https://ncbi.nlm.nih.gov/pubmed/31310630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219507
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