Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients

It is expected that serum protein biomarkers in Duchenne muscular dystrophy (DMD) will reflect disease pathogenesis, progression and aid future therapy developments. Here, we describe use of quantitative in vivo stable isotope labeling in mammals to accurately compare serum proteomes of wild-type an...

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Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Hathout, Yetrib, Marathi, Ramya L., Rayavarapu, Sree, Zhang, Aiping, Brown, Kristy J., Seol, Haeri, Gordish-Dressman, Heather, Cirak, Sebahattin, Bello, Luca, Nagaraju, Kanneboyina, Partridge, Terry, Hoffman, Eric P., Takeda, Shin'ichi, Mah, Jean K., Henricson, Erik, McDonald, Craig
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240201/
https://ncbi.nlm.nih.gov/pubmed/25027324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu366
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