Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive myofiber death in DMD is not fully understood. Using two dystrophin-deficient mdx mouse models, we find that the mitochondrial dysfunction is among the earliest cellular deficits o...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Vila, Maria C, Rayavarapu, Sree, Hogarth, Marshall W, Van der Meulen, Jack H, Horn, Adam, Defour, Aurelia, Takeda, Shin'ichi, Brown, Kristy J, Hathout, Yetrib, Nagaraju, Kanneboyina, Jaiswal, Jyoti K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299714/
https://ncbi.nlm.nih.gov/pubmed/27834955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.127
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