Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive myofiber death in DMD is not fully understood. Using two dystrophin-deficient mdx mouse models, we find that the mitochondrial dysfunction is among the earliest cellular deficits o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Vila, Maria C, Rayavarapu, Sree, Hogarth, Marshall W, Van der Meulen, Jack H, Horn, Adam, Defour, Aurelia, Takeda, Shin'ichi, Brown, Kristy J, Hathout, Yetrib, Nagaraju, Kanneboyina, Jaiswal, Jyoti K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299714/
https://ncbi.nlm.nih.gov/pubmed/27834955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.127
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