Immune-mediated pathology in Duchenne muscular dystrophy

Immunological and inflammatory processes downstream of dystrophin deficiency as well as metabolic abnormalities, defective autophagy, and loss of regenerative capacity all contribute to muscle pathology in Duchenne muscular dystrophy (DMD). These downstream cascades offer potential avenues for pharm...

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Bibliografske podrobnosti
izdano v:Sci Transl Med
Main Authors: Rosenberg, Amy S., Puig, Montserrat, Nagaraju, Kanneboyina, Hoffman, Eric P., Villalta, S. Armando, Rao, V. Ashutosh, Wakefield, Lalage M., Woodcock, Janet
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951380/
https://ncbi.nlm.nih.gov/pubmed/26246170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa7322
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