Orexin Directly Excites Orexin Neurons through Orexin 2 Receptor

Orexin neurons (hypocretin neurons) have a critical role in the regulation of sleep/wakefulness, especially in the maintenance of arousal. Here, we revealed that orexin neurons are directly and indirectly activated by orexin via the orexin 2 receptor (OX2R). Orexin B (1 μm) induced depolarization in...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Yamanaka, Akihiro, Tabuchi, Sawako, Tsunematsu, Tomomi, Fukazawa, Yugo, Tominaga, Makoto
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633594/
https://ncbi.nlm.nih.gov/pubmed/20861370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2120-10.2010
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