Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination

In the developing nervous system, constitutive activation of the AKT/mTOR (mammalian target of rapamycin) pathway in myelinating glial cells is associated with hypermyelination of the brain, but is reportedly insufficient to drive myelination by Schwann cells. We have hypothesized that it requires a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Goebbels, Sandra, Oltrogge, Jan H., Kemper, Robert, Heilmann, Ingo, Bormuth, Ingo, Wolfer, Susanne, Wichert, Sven P., Möbius, Wiebke, Liu, Xin, Lappe-Siefke, Corinna, Rossner, Moritz J., Groszer, Matthias, Suter, Ueli, Frahm, Jens, Boretius, Susann, Nave, Klaus-Armin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632897/
https://ncbi.nlm.nih.gov/pubmed/20592216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0219-10.2010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados