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Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy

‘Tomacula’ and myelin outfoldings are striking neuropathological features of a diverse group of inherited demyelinating neuropathies. Whereas the underlying genetic defects are well known, the molecular mechanisms of tomacula formation have remained obscure. We hypothesized that they are caused by u...

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Detalhes bibliográficos
Main Authors: Goebbels, Sandra, Oltrogge, Jan H, Wolfer, Susanne, Wieser, Georg L, Nientiedt, Tobias, Pieper, Alexander, Ruhwedel, Torben, Groszer, Matthias, Sereda, Michael W, Nave, Klaus-Armin
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443946/
https://ncbi.nlm.nih.gov/pubmed/22488882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200227
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