Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue

Central nervous system myelin is a multilayered membrane sheath generated by oligodendrocytes for rapid impulse propagation. However, the underlying mechanisms of myelin wrapping have remained unclear. Using an integrative approach of live imaging, electron microscopy and genetics, we show that new...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell
Main Authors: Snaidero, Nicolas, Möbius, Wiebke, Czopka, Tim, Hekking, Liesbeth H.P., Mathisen, Cliff, Verkleij, Dick, Goebbels, Sandra, Edgar, Julia, Merkler, Doron, Lyons, David A., Nave, Klaus-Armin, Simons, Mikael
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862569/
https://ncbi.nlm.nih.gov/pubmed/24439382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.044
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares