Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue

Central nervous system myelin is a multilayered membrane sheath generated by oligodendrocytes for rapid impulse propagation. However, the underlying mechanisms of myelin wrapping have remained unclear. Using an integrative approach of live imaging, electron microscopy and genetics, we show that new...

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Vydáno v:Cell
Hlavní autoři: Snaidero, Nicolas, Möbius, Wiebke, Czopka, Tim, Hekking, Liesbeth H.P., Mathisen, Cliff, Verkleij, Dick, Goebbels, Sandra, Edgar, Julia, Merkler, Doron, Lyons, David A., Nave, Klaus-Armin, Simons, Mikael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862569/
https://ncbi.nlm.nih.gov/pubmed/24439382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.044
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