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Cell Depletion Due to Diphtheria Toxin Fragment A after Cre-Mediated Recombination

Abnormal cell loss is the common cause of a large number of developmental and degenerative diseases. To model such diseases in transgenic animals, we have developed a line of mice that allows the efficient depletion of virtually any cell type in vivo following somatic Cre-mediated gene recombination...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brockschnieder, Damian, Lappe-Siefke, Corinna, Goebbels, Sandra, Boesl, Michael R., Nave, Klaus-Armin, Riethmacher, Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC506983/
https://ncbi.nlm.nih.gov/pubmed/15314171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7636-7642.2004
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