Expression and Immunogenicity of a Recombinant Diphtheria Toxin Fragment A in Streptococcus gordonii

A nontoxic mutant diphtheria toxin fragment A (DTA) was genetically fused in single, double, or triple copy to the major surface protein antigen P1 (SpaP) and surface expressed in Streptococcus gordonii DL-1. The expression was verified by Western immunoblotting. Mouse antisera raised against the re...

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Bibliographic Details
Main Authors: Lee, Chiang W., Lee, Song F., Halperin, Scott A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Physiology and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC492408/
https://ncbi.nlm.nih.gov/pubmed/15294787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.8.4569-4574.2004
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