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Notch1 control of oligodendrocyte differentiation in the spinal cord

We have selectively inhibited Notch1 signaling in oligodendrocyte precursors (OPCs) using the Cre/loxP system in transgenic mice to investigate the role of Notch1 in oligodendrocyte (OL) development and differentiation. Early development of OPCs appeared normal in the spinal cord. However, at embryo...

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Détails bibliographiques
Auteurs principaux: Genoud, Stéphane, Lappe-Siefke, Corinna, Goebbels, Sandra, Radtke, Freddy, Aguet, Michel, Scherer, Steven S., Suter, Ueli, Nave, Klaus-Armin, Mantei, Ned
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174019/
https://ncbi.nlm.nih.gov/pubmed/12186854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200202002
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