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In Vivo Genetic Ablation by Cre-Mediated Expression of Diphtheria Toxin Fragment A

We generated a ROSA26-eGFP-DTA mouse line by introducing an eGFP-DTA (enhanced green fluorescent protein - diphtheria toxin fragment A) cassette into the ROSA26 locus by homologous recombination in ES cells. This mouse expresses eGFP ubiquitously, but DTA expression is prevented by the presence of e...

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Detalhes bibliográficos
Main Authors: Ivanova, Anna, Signore, Massimo, Caro, Nadia, Greene, Nicholas D.E., Copp, Andrew J., Martinez-Barbera, Juan Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233880/
https://ncbi.nlm.nih.gov/pubmed/16267821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gene.20162
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