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GSK3β Regulates Myelin-Dependent Axon Outgrowth Inhibition through CRMP4
Myelin-associated inhibitors (MAIs) contribute to failed regeneration in the CNS. The intracellular signaling pathways through which MAIs block axonal repair remain largely unknown. Here, we report that the kinase GSK3β is directly phosphorylated and inactivated by MAIs, consequently regulating prot...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6632347/ https://ncbi.nlm.nih.gov/pubmed/20410116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6154-09.2010 |
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