Dock3 Stimulates Axonal Outgrowth via GSK-3β-Mediated Microtubule Assembly

Dock3, a new member of the guanine nucleotide exchange factors, causes cellular morphological changes by activating the small GTPase Rac1. Overexpression of Dock3 in neural cells promotes axonal outgrowth downstream of brain-derived neurotrophic factor (BDNF) signaling. We previously showed that Doc...

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Vydáno v:J Neurosci
Hlavní autoři: Namekata, Kazuhiko, Harada, Chikako, Guo, Xiaoli, Kimura, Atsuko, Kittaka, Daiji, Watanabe, Hayaki, Harada, Takayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621311/
https://ncbi.nlm.nih.gov/pubmed/22219288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4884-11.2012
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