Extrinsic and intrinsic regulation of axon regeneration at a crossroads

Repair of the injured spinal cord is a major challenge in medicine. The limited intrinsic regenerative response mounted by adult central nervous system (CNS) neurons is further hampered by astrogliosis, myelin debris and scar tissue that characterize the damaged CNS. Improved axon regeneration and r...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Kaplan, Andrew, Ong Tone, Stephan, Fournier, Alyson E.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470051/
https://ncbi.nlm.nih.gov/pubmed/26136657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2015.00027
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