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GSK3β Regulates Myelin-Dependent Axon Outgrowth Inhibition through CRMP4

Myelin-associated inhibitors (MAIs) contribute to failed regeneration in the CNS. The intracellular signaling pathways through which MAIs block axonal repair remain largely unknown. Here, we report that the kinase GSK3β is directly phosphorylated and inactivated by MAIs, consequently regulating prot...

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書目詳細資料
發表在:J Neurosci
Main Authors: Alabed, Yazan Z., Pool, Madeline, Ong Tone, Stephan, Sutherland, Calum, Fournier, Alyson E.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632347/
https://ncbi.nlm.nih.gov/pubmed/20410116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6154-09.2010
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