Growth dynamics in naturally progressing chronic lymphocytic leukaemia

How the genomic features of a patient’s cancer relate to individual disease kinetics remains poorly understood. We leveraged the indolent growth dynamics of chronic lymphocytic leukaemia (CLL) to analyse growth rates and genomic patterns of leukaemia cells from 107 CLL patients, spanning decades-lon...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Gruber, Michaela, Bozic, Ivana, Leshchiner, Ignaty, Livitz, Dimitri, Stevenson, Kristen, Rassenti, Laura, Rosebrock, Daniel, Taylor-Weiner, Amaro, Olive, Oriol, Goyetche, Reaha, Fernandes, Stacey M., Sun, Jing, Stewart, Chip, Wong, Alicia, Cibulskis, Carrie, Zhang, Wandi, Reiter, Johannes G., Gerold, Jeffrey M., Gribben, John G., Rai, Kanti R., Keating, Michael J., Brown, Jennifer R., Neuberg, Donna, Kipps, Thomas J., Nowak, Martin A., Getz, Gad, Wu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630176/
https://ncbi.nlm.nih.gov/pubmed/31142838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1252-x
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