Growth dynamics in naturally progressing chronic lymphocytic leukaemia

How the genomic features of a patient’s cancer relate to individual disease kinetics remains poorly understood. We leveraged the indolent growth dynamics of chronic lymphocytic leukaemia (CLL) to analyse growth rates and genomic patterns of leukaemia cells from 107 CLL patients, spanning decades-lon...

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Publicat a:Nature
Autors principals: Gruber, Michaela, Bozic, Ivana, Leshchiner, Ignaty, Livitz, Dimitri, Stevenson, Kristen, Rassenti, Laura, Rosebrock, Daniel, Taylor-Weiner, Amaro, Olive, Oriol, Goyetche, Reaha, Fernandes, Stacey M., Sun, Jing, Stewart, Chip, Wong, Alicia, Cibulskis, Carrie, Zhang, Wandi, Reiter, Johannes G., Gerold, Jeffrey M., Gribben, John G., Rai, Kanti R., Keating, Michael J., Brown, Jennifer R., Neuberg, Donna, Kipps, Thomas J., Nowak, Martin A., Getz, Gad, Wu, Catherine J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630176/
https://ncbi.nlm.nih.gov/pubmed/31142838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1252-x
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