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Comment on “DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification”

Chen et al. (Reports, 17 February 2017, p. 752) highlight an important problem of sequencing artifacts caused by DNA damage at the time of sample processing. However, their manuscript contains several errors that led the authors to incorrect conclusions. Moreover, the same sequencing artifacts were...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Stewart, Chip, Leshchiner, Ignaty, Hess, Julian, Getz, Gad
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350422/
https://ncbi.nlm.nih.gov/pubmed/30262473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aas9824
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