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Comment on “DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification”

Chen et al. (Reports, 17 February 2017, p. 752) highlight an important problem of sequencing artifacts caused by DNA damage at the time of sample processing. However, their manuscript contains several errors that led the authors to incorrect conclusions. Moreover, the same sequencing artifacts were...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Science
Main Authors: Stewart, Chip, Leshchiner, Ignaty, Hess, Julian, Getz, Gad
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350422/
https://ncbi.nlm.nih.gov/pubmed/30262473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aas9824
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