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Comment on “DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification”

Chen et al. (Reports, 17 February 2017, p. 752) highlight an important problem of sequencing artifacts caused by DNA damage at the time of sample processing. However, their manuscript contains several errors that led the authors to incorrect conclusions. Moreover, the same sequencing artifacts were...

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書目詳細資料
發表在:Science
Main Authors: Stewart, Chip, Leshchiner, Ignaty, Hess, Julian, Getz, Gad
格式: Artigo
語言:Inglês
出版: 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350422/
https://ncbi.nlm.nih.gov/pubmed/30262473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aas9824
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