Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells

Endoplasmic reticulum stress (ER stress) is involved in lipid metabolism and lipotoxicity and can lead to apoptosis. Resveratrol, a sirtuin 1 (SIRT1) agonist, prevents ER stress and improves ER stress-induced hepatic steatosis and cell death. Clusterin is a secreted chaperone and has roles in variou...

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Vydáno v:Cell Stress Chaperones
Hlavní autoři: Lee, Jinmi, Hong, Seok-Woo, Kwon, Hyemi, Park, Se Eun, Rhee, Eun-Jung, Park, Cheol-Young, Oh, Ki-Won, Park, Sung-Woo, Lee, Won-Young
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2019
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629741/
https://ncbi.nlm.nih.gov/pubmed/31183612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-019-01012-z
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