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Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells
BACKGROUND: There is a great need to discover factors that could protect pancreatic β-cells from apoptosis and thus prevent diabetes mellitus. Clusterin (CLU), a chaperone protein, plays an important role in cell protection in numerous cells and is involved in various cellular mechanisms, including...
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| Udgivet i: | Endocrinol Metab (Seoul) |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Korean Endocrine Society
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7803614/ https://ncbi.nlm.nih.gov/pubmed/33261311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2020.768 |
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