Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells

BACKGROUND: The nuclear receptor peroxisome proliferator-activator gamma (PPARγ) is a useful therapeutic target for obesity and diabetes, but its role in protecting β-cell function and viability is unclear. METHODS: To identify the potential functions of PPARγ in β-cells, we treated mouse insulinoma...

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Detalhes bibliográficos
Publicado no:Endocrinol Metab (Seoul)
Main Authors: Hong, Seok-Woo, Lee, Jinmi, Cho, Jung Hwan, Kwon, Hyemi, Park, Se Eun, Rhee, Eun-Jung, Park, Cheol-Young, Oh, Ki-Won, Park, Sung-Woo, Lee, Won-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Endocrine Society 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874186/
https://ncbi.nlm.nih.gov/pubmed/29589392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2018.33.1.105
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