Exendin-4 attenuates endoplasmic reticulum stress through a SIRT1-dependent mechanism

Accumulation of excess hepatic lipids contributes to insulin resistance and liver disease associated with endoplasmic reticulum (ER) stress. Exendin-4 is an agonist of the glucagon-like peptide 1 receptor and plays a role in improving insulin resistance and liver disease by increasing silent mating...

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Hlavní autoři: Lee, Jinmi, Hong, Seok-Woo, Park, Se Eun, Rhee, Eun-Jung, Park, Cheol-Young, Oh, Ki-Won, Park, Sung-Woo, Lee, Won-Young
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2014
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147070/
https://ncbi.nlm.nih.gov/pubmed/24446069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-013-0490-3
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