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Exendin-4 Inhibits Hepatic Lipogenesis by Increasing β-Catenin Signaling

The aim of this study is to investigate whether the beneficial effect of exendin-4 on hepatic steatosis is mediated by β-catenin signaling. After the HepG2 human hepatoma cells were treated with PA for 24 hours, total triglycerides levels were increased in a dose-dependent manner, and the expression...

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Publicado en:PLoS One
Autores principales: Seo, Mi Hae, Lee, Jinmi, Hong, Seok-Woo, Rhee, Eun-Jung, Park, Se Eun, Park, Cheol Young, Oh, Ki Won, Park, Sung Woo, Lee, Won-Young
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131969/
https://ncbi.nlm.nih.gov/pubmed/27907035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166913
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