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Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells
Endoplasmic reticulum stress (ER stress) is involved in lipid metabolism and lipotoxicity and can lead to apoptosis. Resveratrol, a sirtuin 1 (SIRT1) agonist, prevents ER stress and improves ER stress-induced hepatic steatosis and cell death. Clusterin is a secreted chaperone and has roles in variou...
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| Publicado no: | Cell Stress Chaperones |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629741/ https://ncbi.nlm.nih.gov/pubmed/31183612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-019-01012-z |
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