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Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells

Endoplasmic reticulum stress (ER stress) is involved in lipid metabolism and lipotoxicity and can lead to apoptosis. Resveratrol, a sirtuin 1 (SIRT1) agonist, prevents ER stress and improves ER stress-induced hepatic steatosis and cell death. Clusterin is a secreted chaperone and has roles in variou...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Lee, Jinmi, Hong, Seok-Woo, Kwon, Hyemi, Park, Se Eun, Rhee, Eun-Jung, Park, Cheol-Young, Oh, Ki-Won, Park, Sung-Woo, Lee, Won-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629741/
https://ncbi.nlm.nih.gov/pubmed/31183612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-019-01012-z
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